Best Practices For The Safe Handling Of Hazardous Drugs now available in United Kingdom

Published Nov 24, 20
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Safe Handling Of Hazardous Drugs - Children's Minnesota in Meridian-Idaho

Safe Handling of Hazardous Drugs

Competency programs for evaluating safe handling technique have been established using non-toxic products, such as fluorescein, which fluoresces under ultraviolet light, or red dye, which is visible under normal light. (Harrison, 1996). Non-HD solutions should be used for evaluation of preparation technique. Per USP, training should occur prior to preparing or handling HDs, and its effectiveness should be verified by testing specific HD preparation techniques.

Hazardous Chemotherapy

This training should include didactic overview of hazardous drugs, including mutagenic, teratogenic, and carcinogenic properties, and it should include ongoing training for each new HD (USP 797, 2012; USP 800, 2016). USP states that training for compounding personnel should include at least safe aseptic manipulation practices; negative pressure techniques when utilizing a C-PEC and correct use of CSTD devices; containment, cleanup, and disposal procedures for breakages and spills; and treatment of personnel contact and inhalation exposure (USP 797, 2012).

1200] (OSHA, 2012b) as follows: Any operation/procedure in their work area where drugs that present a hazard are present; The location and availability of the written hazard communication program; The location and availability of the list(s) identifying HDs present in the work area; and The location and availability of safety data sheets for all HDs in the work area.

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132]. Training required under the HCS must include all employees potentially exposed to these agents, which includes not only healthcare professional staff, but also physical plant, maintenance, or others who potentially come into contact with the HDs. Staff who may be required to wear respirators must be fit tested and trained to all OSHA respirator requirements (OSHA's RPS, 29 CFR 1910.

Training should include at least the following elements: The properties of the HDs located in the work area; (OSHA, 2011b) The techniques and safe handling practices that have been implemented in the work area to protect employees from exposure to HDs, such as identification of drugs that should be handled as hazardous, appropriate work practices, safety equipment, and PPE to be used, and emergency procedures for spills or employee exposure; (OSHA, 2012b; NIOSH, 2009) The details of the hazard communication program developed by the employer, including an explanation of the labeling and HD identification system used by the employer, the SDSs, and how employees can obtain and use the appropriate hazard information; (OSHA, 2012b) Proper use of safety equipment such as biological safety cabinets, compounding aseptic containment isolators, and closed system transfer devices; (OSHA, 2012b) Proper donning and doffing of PPE; and (OSHA, 2011) Drug preparation, administration, disposal and spill management procedures that minimize worker and environmental exposure (USP 800, 2016).

1020 (OSHA, 2011a). That is, records created in connection with HD handling shall be kept, transferred, and made available for at least 30 years, and medical records shall be kept for the duration of employment plus 30 years. In addition, the HCS does not require training documentation, but sound practice dictates that training records should be created, and include the following information: Dates of the training sessions; Contents or a summary of the training sessions; Names and qualifications of the persons conducting the training; and Names and job titles of all persons attending the training sessions.

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Standard practice for assessment of resistance of medical gloves to permeation by chemotherapy drugs. American International, West Conshohocken, PA: American Society for Testing and Materials. ASTM F739-12 [2012]. Standard test method for resistance of protective clothing materials to permeation by liquids or gases under conditions of continuous contact. West Conshohocken, PA: American Society for Testing and Materials.

Monitoring occupational exposure to cancer chemotherapy drugs. Am J Health Syst Pharm 53(22):2713-23. Balmes JR, Estacio PL, Quinlan P, Kelly T, Corkery K, Blanc P [1995]. Respiratory effects of occupational exposure to aerosolized pentamidine. J Occup Environ Med 37:145-50. Baykal U, Seren S, Sokmen S [2009]. A description of oncology nurses' working conditions in Turkey.